Can fish oil improve mood?

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Summary

Top 9 papers analyzed

These studies suggest that fish oil generally does not have a significant effect on mood, aggression, or depression, but may have some influence on heart rhythm in infants.

Consensus Meter

5 papers analyzed

Percent of Yes answers Yes - 0%

Percent of Possibly answers Possibly - 0%

Percent of No answers No - 100%

12 highly relevant results

There was no effect of 12 weeks of treatment with moderate-dose fish oil supplements on cardiovascular biomarkers or mood in patients with ischemic stroke.

Effects of Moderate-Dose Omega-3 Fish Oil on Cardiovascular Risk Factors and Mood After Ischemic Stroke: A Randomized, Controlled Trial

Stroke

S. Poppitt et al.

2009

RCT

Fish oil exerted few effects in stressful and non-stressful situations, consistent with findings showing little influence of n-3 PUFA supplementation on mood and cognition in young, healthy individuals.

Unknown

Omega-3 fatty acids and stress-induced changes to mood and cognition in healthy individuals

Pharmacology Biochemistry and Behavior

Grace E Giles et al.

2015

RCT

In conclusion, fish oil was no more effective than the control as an add-on therapy for depression in this setting.

Randomised double-blind placebo-controlled trial of fish oil in the treatment of depression.

Prostaglandins, leukotrienes, and essential fatty acids

K. Silvers et al.

2005

RCT

Highly Cited

Fish oil did not significantly influence appetite, tiredness, nausea, well-being, caloric intake, nutritional status, or function after 2 weeks compared with placebo in patients with advanced cancer and loss of both weight and appetite.

Effect of fish oil on appetite and other symptoms in patients with advanced cancer and anorexia/cachexia: a double-blind, placebo-controlled study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

E. Bruera et al.

2003

RCT

Highly Cited

Despite good compliance with oil supplementation, this study found that taking tuna fish oil did not provide any additional benefit to conventional outpatient treatment for major depression in this sample, suggesting that future studies should target participants with pre-existing omega-3 deficiency and appraise alternate enriched types and higher doses of omega-3 supplementation.

Fish oil supplementation in the treatment of major depression: A randomised double-blind placebo-controlled trial

Progress in Neuro-Psychopharmacology and Biological Psychiatry

B. Grenyer et al.

2007

RCT

Highly Cited

In a double-blind study, DHA-rich oil capsules prevented extraggression from increasing at times of mental stress, which could help understand how fish oils prevent diseases like coronary heart disease.

Unknown

The effect of docosahexaenoic acid on aggression in young adults. A placebo-controlled double-blind study.

The Journal of clinical investigation

T. Hamazaki et al.

1996

RCT

Highly Cited

Fish oil treatment does not improve aggression in children with disruptive behavior disorders, according to a randomized, controlled, crossover trial involving twenty-one children (81% male; mean age 10.3±2.2 years; range 7-14).

Unknown

A randomized, controlled, crossover trial of fish oil treatment for impulsive aggression in children and adolescents with disruptive behavior disorders.

Journal of child and adolescent psychopharmacology

A. Dean et al.

2014

RCT